Scurvy – surprisingly not yet extinct

Scurvy Extinct? Think Again!

Scurvy is still seen sporadically in the developed world. Scurvy, a dietary disease due to the deficient intake of vitamin C, is uncommon in the pediatric population. Scurvy occurs as a result of decreased vitamin C consumption or absorption. We present the case of a 6-year-old boy visiting our department with bleeding gums, musculoskeletal pain, and weakness. Four days after starting oral vita...

Lessons (Not Yet) Learned

· Despite a significant influx of charitable dollars over the last 10 to 20 years, solutions to complex social problems remain elusive, while philanthropy has been facing growing pressure to account for its tax-free dollars; to demonstrate, replicate, and scale success; and to be transparent about failed social investments. · When foundations and their nonprofit partners ignore a failure and mo...

Space Weapons: Not Yet

In this paper I attempt to sketch the utility of space weaponry, primarily from the point of view of the United States. In this I draw upon the excellent RAND book, “Space Weapons, Earth Wars.” That study was commissioned by LGen Roger DeKok, DCS Plans and Programs, HQ USAF. I am guided also by the views expressed in presentations and discussions of which I am aware over the past year . But the...

Scurvy

Die—but not just yet

eterochromatin’s repressive hold on DNA transcription can only be relinquished when activators enter the nucleus. Or so the theory goes. But now Vanessa Witte, Andreas Baur (University of Erlangen, Germany), and colleagues find that a heterochromatin component can be pulled from the nucleus by both the HIV protein Nef and activated integrins. “This is a really new concept—that chromatin-associa...